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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM52
All Species:
10.3
Human Site:
S109
Identified Species:
32.38
UniProt:
Q8NDY8
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NDY8
NP_848640.1
209
22122
S109
V
I
P
M
D
S
D
S
P
V
H
S
T
V
T
Chimpanzee
Pan troglodytes
XP_001155815
251
26495
S151
V
I
P
M
D
S
D
S
P
V
H
S
T
V
T
Rhesus Macaque
Macaca mulatta
XP_001097864
379
40235
S279
V
I
P
M
D
S
D
S
P
V
H
S
T
V
T
Dog
Lupus familis
XP_848998
168
18058
L58
G
L
I
L
L
A
V
L
L
L
L
L
C
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D702
196
21034
I97
Q
P
C
D
G
T
V
I
P
V
D
S
D
S
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511416
107
11153
L12
G
E
A
T
L
S
G
L
M
L
C
S
G
P
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090043
213
23385
I97
H
P
C
E
V
T
V
I
A
I
D
N
D
S
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9Y0V2
111
12438
T15
Q
Q
L
R
E
F
L
T
V
Y
N
T
L
S
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
49
70.3
N.A.
66.9
N.A.
N.A.
29.1
N.A.
44.1
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
100
75.3
52.7
72.2
N.A.
70.8
N.A.
N.A.
34.4
N.A.
56.8
N.A.
N.A.
N.A.
N.A.
32
N.A.
P-Site Identity:
100
100
100
0
N.A.
20
N.A.
N.A.
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
26.6
N.A.
N.A.
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
0
0
13
0
0
13
0
0
0
0
0
0
% A
% Cys:
0
0
25
0
0
0
0
0
0
0
13
0
13
0
0
% C
% Asp:
0
0
0
13
38
0
38
0
0
0
25
0
25
0
0
% D
% Glu:
0
13
0
13
13
0
0
0
0
0
0
0
0
0
13
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
25
0
0
0
13
0
13
0
0
0
0
0
13
13
0
% G
% His:
13
0
0
0
0
0
0
0
0
0
38
0
0
0
0
% H
% Ile:
0
38
13
0
0
0
0
25
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
13
13
13
25
0
13
25
13
25
13
13
13
0
0
% L
% Met:
0
0
0
38
0
0
0
0
13
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
13
13
0
0
0
% N
% Pro:
0
25
38
0
0
0
0
0
50
0
0
0
0
13
13
% P
% Gln:
25
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
50
0
38
0
0
0
63
0
38
13
% S
% Thr:
0
0
0
13
0
25
0
13
0
0
0
13
38
0
50
% T
% Val:
38
0
0
0
13
0
38
0
13
50
0
0
0
38
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _